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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CTH Antibody (monoclonal) (M03)   

CTH Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a full length recombinant CTH.

  • WB - CTH Antibody (monoclonal) (M03) AT1668a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (70.07 KDa) .
  • WB - CTH Antibody (monoclonal) (M03) AT1668a
    CTH monoclonal antibody (M03), clone S51. Western Blot analysis of CTH expression in mouse kidney.
  • WB - CTH Antibody (monoclonal) (M03) AT1668a
    CTH monoclonal antibody (M03), clone S51 Western Blot analysis of CTH expression in K-562 ( (Cat # AT1668a )
  • WB - CTH Antibody (monoclonal) (M03) AT1668a
    Western Blot analysis of CTH expression in transfected 293T cell line by CTH monoclonal antibody (M03), clone S51.

    Lane 1: CTH transfected lysate(45 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - CTH Antibody (monoclonal) (M03) AT1668a
    Immunoperoxidase of monoclonal antibody to CTH on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
  • E - CTH Antibody (monoclonal) (M03) AT1668a
    Detection limit for recombinant GST tagged CTH is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32929
Other Accession BC015807
Reactivity Human, Mouse
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names S51
Calculated MW 44508 Da
Additional Information
Gene ID 1491
Other Names Cystathionine gamma-lyase, Cysteine-protein sulfhydrase, Gamma-cystathionase, CTH
Target/Specificity CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCTH Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.


1.cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation.Bucci M, Papapetropoulos A, Vellecco V, Zhou Z, Zaid A, Giannogonas P, Cantalupo A, Dhayade S, Karalis KP, Wang R, Feil R, Cirino G.PLoS One. 2012;7(12):e53319. doi: 10.1371/journal.pone.0053319. Epub 2012 Dec 28.2.Hydrogen sulfide impairs glucose utilization and increases gluconeogenesis in hepatocytes.Zhang L, Yang G, Untereiner A, Ju Y, Wu L, Wang R.Endocrinology. 2013 Jan;154(1):114-26. doi: 10.1210/en.2012-1658. Epub 2012 Nov 26.3.An investigation of the mechanisms of hydrogen sulfide-induced vasorelaxation in rat middle cerebral arteries.Streeter E, Hart J, Badoer E.Naunyn Schmiedebergs Arch Pharmacol. 2012 Jul 17.4.Characterization of Hydrogen Sulfide and Its Synthases, Cystathionine ?]-Synthase and Cystathionine ?^-Lyase, in Human Prostatic Tissue and Cells.Guo H, Gai JW, Wang Y, Jin HF, Du JB, Jin J.Urology. 2012 Feb;79(2):483.e1-5.5.Glucocorticoids suppress cystathionine gamma-lyase expression and H(2)S production in lipopolysaccharide-treated macrophages.Zhu XY, Liu SJ, Liu YJ, Wang S, Ni X.Cell Mol Life Sci. 2010 Jan 10. [Epub ahead of print]6.H2S contributes to the hepatic arterial buffer response and mediates vasorelaxation of the hepatic artery via activation of KATP channels.Siebert N, Cantre D, Eipel C, Vollmar B.Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1266-73. Epub 2008 Oct 30.

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$ 315.00
Cat# AT1668a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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