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DIABLO Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant DIABLO.

  • WB - DIABLO Antibody (monoclonal) (M02) AT1763a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - DIABLO Antibody (monoclonal) (M02) AT1763a
    Western Blot analysis of DIABLO expression in transfected 293T cell line by DIABLO monoclonal antibody (M02), clone 4F9.

    Lane 1: DIABLO transfected lysate(27.131 KDa).
    Lane 2: Non-transfected lysate.
  • E - DIABLO Antibody (monoclonal) (M02) AT1763a
    Detection limit for recombinant GST tagged DIABLO is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NR28
Other Accession BC011909
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4F9
Calculated MW 27131 Da
Additional Information
Gene ID 56616
Other Names Diablo homolog, mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase, Smac, DIABLO, SMAC
Target/Specificity DIABLO (AAH11909, 119 a.a. ~ 218 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsDIABLO Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Overexpression of Smac/DIABLO in Hep-2 cell line: possible role in potentiating the sensitivity of chemotherapeutic drugs. Lu S, et al. Tumori, 2010 Mar-Apr. PMID 20572591.Hip2 interacts with and destabilizes Smac/DIABLO. Bae Y, et al. Biochem Biophys Res Commun, 2010 Jul 9. PMID 20537984.Survivin and Smac gene expressions but not livin are predictors of prognosis in non-small cell lung cancer patients treated with adjuvant chemotherapy following surgery. Dai CH, et al. Jpn J Clin Oncol, 2010 Apr. PMID 20056675.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.

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$ 315.00
Cat# AT1763a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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