DPYSL5 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant DPYSL5.
|Application ||WB, E|
|Calculated MW||61421 Da|
|Other Names||Dihydropyrimidinase-related protein 5, DRP-5, CRMP3-associated molecule, CRAM, Collapsin response mediator protein 5, CRMP-5, UNC33-like phosphoprotein 6, ULIP-6, DPYSL5, CRMP5, ULIP6|
|Target/Specificity||DPYSL5 (NP_064519, 466 a.a. ~ 564 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||DPYSL5 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Members of the CRMP family, such as DPYSL5, are believed to play a role in growth cone guidance during neural development.
Onco-neural antibodies and tumour type determine survival and neurological symptoms in paraneoplastic neurological syndromes with Hu or CV2/CRMP5 antibodies. Honnorat J, et al. J Neurol Neurosurg Psychiatry, 2009 Apr. PMID 18931014.Extensive expression of collapsin response mediator protein 5 (CRMP5) is a specific marker of high-grade lung neuroendocrine carcinoma. Meyronet D, et al. Am J Surg Pathol, 2008 Nov. PMID 18769332.High-titer collapsin response-mediating protein-associated (CRMP-5) paraneoplastic optic neuropathy and Vitritis as the only clinical manifestations in a patient with small cell lung carcinoma. Margolin E, et al. J Neuroophthalmol, 2008 Mar. PMID 18347453.Autoimmune myelopathy associated with collapsin response-mediator protein-5 immunoglobulin G. Keegan BM, et al. Ann Neurol, 2008 Apr. PMID 18306241.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.
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