DTX3L Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant DTX3L.
|Application ||WB, IHC, E|
|Calculated MW||83554 Da|
|Other Names||E3 ubiquitin-protein ligase DTX3L, 632-, B-lymphoma- and BAL-associated protein, Protein deltex-3-like, Rhysin-2, Rhysin2, DTX3L, BBAP|
|Target/Specificity||DTX3L (NP_612144, 3 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||DTX3L Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
DTX3L functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).
BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response. Yan Q, et al. Mol Cell, 2009 Oct 9. PMID 19818714.Integrated genomic and transcriptional profiling identifies chromosomal loci with altered gene expression in cervical cancer. Wilting SM, et al. Genes Chromosomes Cancer, 2008 Oct. PMID 18618715.BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate. Juszczynski P, et al. Mol Cell Biol, 2006 Jul. PMID 16809771.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.
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