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>   home   >   Products   >   Primary Antibodies   >   DYM Antibody (monoclonal) (M01)   

DYM Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant DYM.

     
  • E - DYM Antibody (monoclonal) (M01) AT1833a
    Detection limit for recombinant GST tagged DYM is approximately 1ng/ml as a capture antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
E
Primary Accession Q7RTS9
Other Accession NM_017653
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1C2
Calculated MW 75935 Da
Additional Information
Gene ID 54808
Other Names Dymeclin, Dyggve-Melchior-Clausen syndrome protein, DYM
Target/Specificity DYM (NP_060123, 343 a.a. ~ 430 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsDYM Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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Background

This gene encodes a protein which is necessary for normal skeletal development and brain function. Mutations in this gene are associated with two types of recessive osteochondrodysplasia, Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia, which involve both skeletal defects and mental retardation.

References

An association study between the dymeclin gene and schizophrenia in the Japanese population. Yazaki S, et al. J Hum Genet, 2010 Sep. PMID 20555340.The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. Zhao J, et al. BMC Med Genet, 2010 Jun 14. PMID 20546612.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.The gene responsible for Dyggve-Melchior-Clausen syndrome encodes a novel peripheral membrane protein dynamically associated with the Golgi apparatus. Dimitrov A, et al. Hum Mol Genet, 2009 Feb 1. PMID 18996921.Genome-wide association analysis identifies 20 loci that influence adult height. Weedon MN, et al. Nat Genet, 2008 May. PMID 18391952.

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$ 315.00
Cat# AT1833a
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