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ELK3 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant ELK3.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P41970 |
| Other Accession | NM_005230 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3A12 |
| Calculated MW | 44240 Da |
| Gene ID | 2004 |
|---|---|
| Other Names | ETS domain-containing protein Elk-3, ETS-related protein ERP, ETS-related protein NET, Serum response factor accessory protein 2, SAP-2, SRF accessory protein 2, ELK3, NET, SAP2 |
| Target/Specificity | ELK3 (NP_005221.2, 101 a.a. ~ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ELK3 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.
References
Involvement of net and Hif1alpha in distinct yet intricately linked hypoxia-induced signaling pathways. Serchov T, et al. J Biol Chem, 2010 Jul 9. PMID 20427288.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Growth inhibitory effect of the ternary complex factor Net on human pancreatic carcinoma cell lines. Li B, et al. Tohoku J Exp Med, 2008 Oct. PMID 18832796.Inhibition of the Ras-Net (Elk-3) pathway by a novel pyrazole that affects microtubules. Wasylyk C, et al. Cancer Res, 2008 Mar 1. PMID 18316589.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
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