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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ErbB2IP   


Mouse monoclonal antibody raised against a partial recombinant ERBB2IP.

  • WB - ErbB2IP AT1935a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • E - ErbB2IP AT1935a
    Detection limit for recombinant GST tagged ERBB2IP is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96RT1
Other Accession NM_018695
Reactivity Human
Host mouse
Clonality monoclonal
Isotype IgG2a Kappa
Clone Names 10G1
Calculated MW 158298 Da
Additional Information
Gene ID 55914
Other Names Protein LAP2, Densin-180-like protein, Erbb2-interacting protein, Erbin, ERBB2IP, ERBIN, KIAA1225, LAP2
Target/Specificity ERBB2IP (NP_061165, 1272 a.a. ~ 1371 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsErbB2IP is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date.


Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Densin-180: revised membrane topology, domain structure and phosphorylation status. Thalhammer A, et al. J Neurochem, 2009 Apr. PMID 19187442.Biochemical studies and molecular dynamics simulations of Smad3-Erbin interaction identify a non-classical Erbin PDZ binding. D?liot N, et al. Biochem Biophys Res Commun, 2009 Jan 16. PMID 19013433.The PDZ protein erbin modulates beta-catenin-dependent transcription. Ress A, et al. Eur Surg Res, 2008. PMID 18667832.Palmitoylation of ERBIN is required for its plasma membrane localization. Izawa I, et al. Genes Cells, 2008 Jul. PMID 18498353.

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$ 315.00
Cat# AT1935a
(40 western blots)
Availability: 7-10 days
Bulk Size
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