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ERCC2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant ERCC2.

     
  • WB - ERCC2 Antibody (monoclonal) (M01) AT1937a
    Western Blot analysis of ERCC2 expression in transfected 293T cell line by ERCC2 monoclonal antibody (M01), clone 4G2-2A6.

    Lane 1: ERCC2 transfected lysate(86.9 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • WB - ERCC2 Antibody (monoclonal) (M01) AT1937a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (70.29 KDa) .
    detail
  • WB - ERCC2 Antibody (monoclonal) (M01) AT1937a
    ERCC2 monoclonal antibody (M01), clone 4G2-2A6 Western Blot analysis of ERCC2 expression in Hela S3 NE ( (Cat # AT1937a )
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P18074
Other Accession BC008346
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 4G2-2A6
Calculated MW 86909 Da
Additional Information
Gene ID 2068
Other Names TFIIH basal transcription factor complex helicase XPD subunit, Basic transcription factor 2 80 kDa subunit, BTF2 p80, CXPD, DNA excision repair protein ERCC-2, DNA repair protein complementing XP-D cells, TFIIH basal transcription factor complex 80 kDa subunit, TFIIH 80 kDa subunit, TFIIH p80, Xeroderma pigmentosum group D-complementing protein, ERCC2, XPD, XPDC
Target/Specificity ERCC2 (AAH08346, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsERCC2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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citation

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Background

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

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$ 350.00
Cat# AT1937a
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