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ESR2 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT1950a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
ESR2 Antibody (monoclonal) (M01) - Product info | |
| Primary Accession | Q92731 |
| Other Accession | NP_001428 |
| Reactivity | Human |
| Isotype | IgG2b Kappa |
| Clone Names | 3F3 |
| Calculated MW | 59216 Da |
ESR2 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 2100 | |
| Other Names 5p152, ERBETA, ESRBETA, ESRB, Erb, NR3A2estrogen receptor 2 (ER beta) | |
| Target/Specificity ESR2 (NP_001428, 22 a.a. ~ 122 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ESR2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ESR2 Antibody (monoclonal) (M01) - Related products
AP1702c: ESR2 Antibody (Center)
ESR2 Antibody (monoclonal) (M01) - Application data
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Detection limit for recombinant GST tagged ESR2 is approximately 0.3ng/ml as a capture antibody.
ESR2 Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
REFERENCES
A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Romero R, et al. Am J Obstet Gynecol, 2010 Jul 29. PMID 20673868.Haplotypes of estrogen receptor-beta and risk of non-small cell lung cancer in women. Paulus JK, et al. Lung Cancer, 2010 Jul 22. PMID 20655613.Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium. Canzian F, et al. Hum Mol Genet, 2010 Oct 1. PMID 20634197.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
