FBLN1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant FBLN1.
|Application ||WB, IP|
|Calculated MW||77214 Da|
|Other Names||Fibulin-1, FIBL-1, FBLN1|
|Target/Specificity||FBLN1 (AAH22497, 151 a.a. ~ 250 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||FBLN1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
All-trans retinoic acid regulates the expression of the extracellular matrix protein fibulin-1 in the guinea pig sclera and human scleral fibroblasts. Li C, et al. Mol Vis, 2010 Apr 15. PMID 20405022.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Application of gene network analysis techniques identifies AXIN1/PDIA2 and endoglin haplotypes associated with bicuspid aortic valve. Wooten EC, et al. PLoS One, 2010 Jan 21. PMID 20098615.Fibulin-1 and fibrinogen in human atherosclerotic lesions. Argraves WS, et al. Histochem Cell Biol, 2009 Nov. PMID 19693531.Expression of ECM proteins fibulin-1 and -2 in acute and chronic liver disease and in cultured rat liver cells. Piscaglia F, et al. Cell Tissue Res, 2009 Sep. PMID 19609566.
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