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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FCGR3A Antibody (monoclonal) (M03)   

FCGR3A Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a full-length recombinant FCGR3A.

  • WB - FCGR3A Antibody (monoclonal) (M03) AT2028a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (51.92 KDa) .
  • WB - FCGR3A Antibody (monoclonal) (M03) AT2028a
    FCGR3A monoclonal antibody (M03), clone 2B11. Western Blot analysis of FCGR3A expression in Jurkat ( (Cat # AT2028a )
  • E - FCGR3A Antibody (monoclonal) (M03) AT2028a
    Detection limit for recombinant GST tagged FCGR3A is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08637
Other Accession BC017865
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2B11
Calculated MW 29089 Da
Additional Information
Gene ID 2214
Other Names Low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, IGFR3
Target/Specificity FCGR3A (AAH17865.1, 17 a.a. ~ 254 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFCGR3A Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.


[Fcgamma ReceptorIIIa Polymorphism in Healthy Children and Those with Hematological Malignancies.] Qu YH, et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2010 Jul. PMID 20723308.Functional polymorphisms of PTPN22 and FcgR genes in Tunisian patients with rheumatoid arthritis. Sfar I, et al. Arch Inst Pasteur Tunis, 2009. PMID 20707220.Effect of FCGR2A and FCGR3A variants on CLL outcome. Dornan D, et al. Blood, 2010 Aug 12. PMID 20705761.Fragment c gamma receptor gene polymorphisms and breast cancer risk in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians. Iwasaki M, et al. Breast Cancer Res Treat, 2010 Aug 10. PMID 20697800.The loss of the CD16 B73.1/Leu11c epitope occurring in some primary immunodeficiency diseases is not associated with the FcgammaRIIIa-48L/R/H polymorphism. Lenart M, et al. Int J Mol Med, 2010 Sep. PMID 20664961.

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$ 315.00
Cat# AT2028a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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