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FHL2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant FHL2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF |
|---|---|
| Primary Accession | Q14192 |
| Other Accession | BC014397 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 2G3-1A5 |
| Calculated MW | 32193 Da |
| Gene ID | 2274 |
|---|---|
| Other Names | Four and a half LIM domains protein 2, FHL-2, LIM domain protein DRAL, Skeletal muscle LIM-protein 3, SLIM-3, FHL2, DRAL, SLIM3 |
| Target/Specificity | FHL2 (AAH14397, 1 a.a. ~ 279 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | FHL2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
LIM proteins contain a highly conserved double zinc finger motif called the LIM domain.
References
Sp1 upregulates the four and half lim 2 (FHL2) expression in gastrointestinal cancers through transcription regulation. Guo Z, et al. Mol Carcinog, 2010 Sep. PMID 20607723.Four-and-a-half LIM domain protein 2 is a novel regulator of sphingosine 1-phosphate receptor 1 in CCL19-induced dendritic cell migration. K?nig K, et al. J Immunol, 2010 Aug 1. PMID 20592280.Four-and-a-half LIM protein 2 promotes invasive potential and epithelial-mesenchymal transition in colon cancer. Zhang W, et al. Carcinogenesis, 2010 Jul. PMID 20460358.Four and a half LIM domain 2 alters the impact of aryl hydrocarbon receptor on androgen receptor transcriptional activity. Kollara A, et al. J Steroid Biochem Mol Biol, 2010 Jan. PMID 19815066.The Patched dependence receptor triggers apoptosis through a DRAL-caspase-9 complex. Mille F, et al. Nat Cell Biol, 2009 Jun. PMID 19465923.
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