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FIS1 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a full-length recombinant FIS1.

  • WB - FIS1 Antibody (monoclonal) (M02) AT2053a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (42.46 KDa) .
  • WB - FIS1 Antibody (monoclonal) (M02) AT2053a
    FIS1 monoclonal antibody (M02), clone 3G6. Western Blot analysis of FIS1 expression in MCF-7 ( (Cat # AT2053a )
  • E - FIS1 Antibody (monoclonal) (M02) AT2053a
    Detection limit for recombinant GST tagged FIS1 is 0.1 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y3D6
Other Accession BC003540
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 3G6
Calculated MW 16938 Da
Additional Information
Gene ID 51024
Other Names Mitochondrial fission 1 protein, FIS1 homolog, hFis1, Tetratricopeptide repeat protein 11, TPR repeat protein 11, FIS1, TTC11
Target/Specificity FIS1 (AAH03540.1, 1 a.a. ~ 152 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFIS1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission (James et al., 2003 [PubMed 12783892]).


Specific mitochondrial calcium overload induces mitochondrial fission in prostate cancer cells. Kaddour-Djebbar I, et al. Int J Oncol, 2010 Jun. PMID 20428767.Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1. Mai S, et al. J Cell Sci, 2010 Mar 15. PMID 20179104.Identification and characterization of unique proline-rich peptides binding to the mitochondrial fission protein hFis1. Serasinghe MN, et al. J Biol Chem, 2010 Jan 1. PMID 19864424.The mitochondrial outer membrane protein hFis1 regulates mitochondrial morphology and fission through self-interaction. Serasinghe MN, et al. Exp Cell Res, 2008 Nov 15. PMID 18845145.Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells. Park KS, et al. J Biol Chem, 2008 Nov 28. PMID 18832378.

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$ 315.00
Cat# AT2053a
(40 western blots)
Availability: 7-10 days
Bulk Size
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