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FOXA2 Antibody (monoclonal) (M10)

Mouse monoclonal antibody raised against a partial recombinant FOXA2.

  • WB - FOXA2 Antibody (monoclonal) (M10) AT2086a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.19 KDa) .
  • WB - FOXA2 Antibody (monoclonal) (M10) AT2086a
    FOXA2 monoclonal antibody (M10), clone 1C7 Western Blot analysis of FOXA2 expression in HepG2 ( (Cat # AT2086a )
  • IHC - FOXA2 Antibody (monoclonal) (M10) AT2086a
    Immunoperoxidase of monoclonal antibody to FOXA2 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 1 ug/ml]
  • IF - FOXA2 Antibody (monoclonal) (M10) AT2086a
    Immunofluorescence of monoclonal antibody to FOXA2 on HepG2 cell. [antibody concentration 10 ug/ml]
  • IP - FOXA2 Antibody (monoclonal) (M10) AT2086a
    Immunoprecipitation of FOXA2 transfected lysate using anti-FOXA2 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with FOXA2 MaxPab rabbit polyclonal antibody.
  • E - FOXA2 Antibody (monoclonal) (M10) AT2086a
    Detection limit for recombinant GST tagged FOXA2 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y261
Other Accession NM_021784
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1C7
Calculated MW 48306 Da
Additional Information
Gene ID 3170
Other Names Hepatocyte nuclear factor 3-beta, HNF-3-beta, HNF-3B, Forkhead box protein A2, Transcription factor 3B, TCF-3B, FOXA2, HNF3B, TCF3B
Target/Specificity FOXA2 (NP_068556, 363 a.a. ~ 457 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFOXA2 Antibody (monoclonal) (M10) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Foxa2 (HNF-3beta) regulates expression of hepatotrophic factor ALR in liver cells. Dayoub R, et al. Biochem Biophys Res Commun, 2010 May 14. PMID 20382118.Hepatitis C virus differentially modulates activation of forkhead transcription factors and insulin-induced metabolic gene expression. Banerjee A, et al. J Virol, 2010 Jun. PMID 20357092.Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer. Song Y, et al. Cancer Res, 2010 Mar 1. PMID 20160041.A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels. Xing C, et al. Am J Hum Genet, 2010 Mar 12. PMID 20152958.

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$ 315.00
Cat# AT2086a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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