FOXD1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant FOXD1.
|Application ||WB, E|
|Calculated MW||46140 Da|
|Other Names||Forkhead box protein D1, Forkhead-related protein FKHL8, Forkhead-related transcription factor 4, FREAC-4, FOXD1, FKHL8, FREAC4|
|Target/Specificity||FOXD1 (NP_004463, 1 a.a. ~ 91 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||FOXD1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This intronless gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in tumor formation.
Smad6s regulates plasminogen activator inhibitor-1 through a protein kinase C-beta-dependent up-regulation of transforming growth factor-beta. Berg DT, et al. J Biol Chem, 2005 Apr 15. PMID 15716278.Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12). Larsson C, et al. Genomics, 1995 Dec 10. PMID 8825632.Characterization of the human forkhead gene FREAC-4. Evidence for regulation by Wilms' tumor suppressor gene (WT-1) and p53. Ernstsson S, et al. J Biol Chem, 1996 Aug 30. PMID 8702877.Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending. Pierrou S, et al. EMBO J, 1994 Oct 17. PMID 7957066.
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