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FTS Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a full length recombinant FTS.

  • WB - FTS Antibody (monoclonal) (M02) AT2116a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (57.86 KDa) .
  • WB - FTS Antibody (monoclonal) (M02) AT2116a
    Western Blot analysis of FTS expression in transfected 293T cell line by FTS monoclonal antibody (M02), clone 2A11.

    Lane 1: FTS transfected lysate(33.1 KDa).
    Lane 2: Non-transfected lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H8T0
Other Accession BC001134
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2A11
Calculated MW 33128 Da
Additional Information
Gene ID 64400
Other Names AKT-interacting protein, Ft1, Fused toes protein homolog, AKTIP, FTS
Target/Specificity FTS (AAH01134, 1 a.a. ~ 292 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFTS Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.


Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer. Notaridou M, et al. Int J Cancer, 2010 Jul 15. PMID 20635389.Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival. Quaye L, et al. Hum Mol Genet, 2009 May 15. PMID 19270026.An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex. Xu L, et al. Mol Biol Cell, 2008 Dec. PMID 18799622.Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.

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$ 315.00
Cat# AT2116a
(40 western blots)
Availability: 7-10 days
Bulk Size
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