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G22P1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant XRCC6.

  • WB - G22P1 Antibody (monoclonal) (M01) AT2136a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (92.73 KDa) .
  • WB - G22P1 Antibody (monoclonal) (M01) AT2136a
    XRCC6 monoclonal antibody (M01), clone 4C2-1A6 Western Blot analysis of XRCC6 expression in C32 ( (Cat # AT2136a )
  • WB - G22P1 Antibody (monoclonal) (M01) AT2136a
    Western Blot analysis of XRCC6 expression in transfected 293T cell line by G22P1 monoclonal antibody (M01), clone 4C2-1A6.

    Lane 1: XRCC6 transfected lysate(70 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - G22P1 Antibody (monoclonal) (M01) AT2136a
    Immunoperoxidase of monoclonal antibody to XRCC6 on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 3 ug/ml]
  • IF - G22P1 Antibody (monoclonal) (M01) AT2136a
    Immunofluorescence of monoclonal antibody to XRCC6 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - G22P1 Antibody (monoclonal) (M01) AT2136a
    Detection limit for recombinant GST tagged XRCC6 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P12956
Other Accession BC008343
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 4C2-1A6
Calculated MW 69843 Da
Additional Information
Gene ID 2547
Other Names X-ray repair cross-complementing protein 6, 364-, 4299-, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Ku70, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 6, XRCC6, G22P1
Target/Specificity XRCC6 (AAH08343.1, 1 a.a. ~ 609 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsG22P1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.


1.DNA-PKcs Expression Predicts Response to Radiotherapy in Prostate Cancer.Bouchaert P, Guerif S, Debiais C, Irani J, Fromont G.Int J Radiat Oncol Biol Phys. 2012 Apr 10. [Epub ahead of print]2.Myonuclear breakdown in sporadic inclusion body myositis is accompanied by DNA double strand breaks.Nishii M, Nakano S, Nakamura S, Wate R, Shinde A, Kaneko S, Kusaka H.Neuromuscul Disord. 2011 Feb 23. [Epub ahead of print]

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$ 315.00
Cat# AT2136a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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