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>   home   >   Products   >   Primary Antibodies   >   GEMIN6 Antibody (monoclonal) (M08)   

GEMIN6 Antibody (monoclonal) (M08)

Mouse monoclonal antibody raised against a full length recombinant GEMIN6.

  • WB - GEMIN6 Antibody (monoclonal) (M08) AT2189a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (44.11 KDa) .
  • E - GEMIN6 Antibody (monoclonal) (M08) AT2189a
    Detection limit for recombinant GST tagged GEMIN6 is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WXD5
Other Accession BC018195
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 3D2
Calculated MW 18824 Da
Additional Information
Gene ID 79833
Other Names Gem-associated protein 6, Gemin-6, SIP2, GEMIN6
Target/Specificity GEMIN6 (AAH18195, 1 a.a. ~ 167 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsGEMIN6 Antibody (monoclonal) (M08) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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GEMIN6 is part of a large macromolecular complex, localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1; MIM 602595), GEMIN3 (DDX20; MIM 606168), GEMIN4 (MIM 606969), and GEMIN5 (MIM 607005).


Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Svendsen JM, et al. Cell, 2009 Jul 10. PMID 19596235.Gemin8 is required for the architecture and function of the survival motor neuron complex. Carissimi C, et al. J Biol Chem, 2006 Dec 1. PMID 17023415.Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.The Gemin6-Gemin7 heterodimer from the survival of motor neurons complex has an Sm protein-like structure. Ma Y, et al. Structure, 2005 Jun. PMID 15939020.Unrip is a component of SMN complexes active in snRNP assembly. Carissimi C, et al. FEBS Lett, 2005 Apr 25. PMID 15848170.

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$ 315.00
Cat# AT2189a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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