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GGPS1 Antibody (monoclonal) (M08)

Mouse monoclonal antibody raised against a partial recombinant GGPS1.

  • WB - GGPS1 Antibody (monoclonal) (M08) AT2196a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • E - GGPS1 Antibody (monoclonal) (M08) AT2196a
    Detection limit for recombinant GST tagged GGPS1 is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95749
Other Accession NM_004837
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 1C3
Calculated MW 34871 Da
Additional Information
Gene ID 9453
Other Names Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, 251-, (2E, 6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, GGPS1
Target/Specificity GGPS1 (NP_004828, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsGGPS1 Antibody (monoclonal) (M08) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene.


Genetic polymorphism of geranylgeranyl diphosphate synthase (GGSP1) predicts bone density response to bisphosphonate therapy in Korean women. Choi HJ, et al. Yonsei Med J, 2010 Mar 1. PMID 20191015.cDNA cloning, chromosome mapping and expression characterization of human geranylgeranyl pyrophosphate synthase. Zhao Y, et al. Sci China C Life Sci, 2000 Dec. PMID 18726356.Human geranylgeranyl diphosphate synthase is an octamer in solution. Miyagi Y, et al. J Biochem, 2007 Sep. PMID 17646172.Farnesyl transferase inhibitor resistance probed by target mutagenesis. Raz T, et al. Blood, 2007 Sep 15. PMID 17536018.Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects. Ma J, et al. Atherosclerosis, 2007 Mar. PMID 16806233.

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$ 315.00
Cat# AT2196a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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