GLB1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant GLB1.
|Application ||WB, IP|
|Calculated MW||76075 Da|
|Other Names||Beta-galactosidase, Acid beta-galactosidase, Lactase, Elastin receptor 1, GLB1, ELNR1|
|Target/Specificity||GLB1 (NP_000395, 578 a.a. ~ 677 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||GLB1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Multiple common variants for celiac disease influencing immune gene expression. Dubois PC, et al. Nat Genet, 2010 Apr. PMID 20190752.Role of the elastin receptor complex (S-Gal/Cath-A/Neu-1) in skin repair and regeneration. Antonicelli F, et al. Wound Repair Regen, 2009 Sep-Oct. PMID 19769716.GM1 gangliosidosis and Morquio B disease: expression analysis of missense mutations affecting the catalytic site of acid beta-galactosidase. Hofer D, et al. Hum Mutat, 2009 Aug. PMID 19472408.New GLB1 mutation in siblings with Morquio type B disease presenting with mental regression. Mayer FQ, et al. Mol Genet Metab, 2009 Mar. PMID 19091613.
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