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GMEB1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant GMEB1.

  • WB - GMEB1 Antibody (monoclonal) (M01) AT2217a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.41 KDa) .
  • WB - GMEB1 Antibody (monoclonal) (M01) AT2217a
    GMEB1 monoclonal antibody (M01), clone 2A8 Western Blot analysis of GMEB1 expression in Hela S3 NE ( (Cat # AT2217a )
  • IHC - GMEB1 Antibody (monoclonal) (M01) AT2217a
    Immunoperoxidase of monoclonal antibody to GMEB1 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml]
  • IF - GMEB1 Antibody (monoclonal) (M01) AT2217a
    Immunofluorescence of monoclonal antibody to GMEB1 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - GMEB1 Antibody (monoclonal) (M01) AT2217a
    Detection limit for recombinant GST tagged GMEB1 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y692
Other Accession NM_024482
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2A8
Calculated MW 62591 Da
Additional Information
Gene ID 10691
Other Names Glucocorticoid modulatory element-binding protein 1, GMEB-1, DNA-binding protein p96PIF, Parvovirus initiation factor p96, PIF p96, GMEB1
Target/Specificity GMEB1 (NP_077808, 467 a.a. ~ 563 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsGMEB1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene is a member of KDWK gene family. The product of this gene associates with GMEB2 protein, and the complex is essential for parvovirus DNA replication. Study of rat homolog implicates the role of this gene in modulation of transactivation by the glucocorticoid receptor bound to glucocorticoid response elements. Two alternative spliced transcript variants encoding different isoforms exist.


GMEB1, a novel endogenous caspase inhibitor, prevents hypoxia- and oxidative stress-induced neuronal apoptosis. Nakagawa T, et al. Neurosci Lett, 2008 Jun 13. PMID 18455874.Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis. Koyama S, et al. J Mol Biol, 2008 Mar 7. PMID 18222470.A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Beausoleil SA, et al. Nat Biotechnol, 2006 Oct. PMID 16964243.Glucocorticoid modulatory element-binding protein 1 binds to initiator procaspases and inhibits ischemia-induced apoptosis and neuronal injury. Tsuruma K, et al. J Biol Chem, 2006 Apr 21. PMID 16497673.Regulation of procaspase-2 by glucocorticoid modulatory element-binding protein 1 through the interaction with caspase recruitment domain. Tsuruma K, et al. Biochem Biophys Res Commun, 2004 Dec 24. PMID 15555560.

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$ 315.00
Cat# AT2217a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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