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GSDML Antibody (monoclonal) (M05)

Mouse monoclonal antibody raised against a full-length recombinant GSDML.

  • WB - GSDML Antibody (monoclonal) (M05) AT2270a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (70.95 KDa) .
  • WB - GSDML Antibody (monoclonal) (M05) AT2270a
    GSDML monoclonal antibody (M05), clone 1E10. Western Blot analysis of GSDML expression in A-431 ( (Cat # AT2270a )
  • IF - GSDML Antibody (monoclonal) (M05) AT2270a
    Immunofluorescence of monoclonal antibody to GSDMB on HeLa cell . [antibody concentration 20 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TAX9
Other Accession BC025682
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1E11
Calculated MW 46786 Da
Additional Information
Gene ID 55876
Other Names Gasdermin-B, Gasdermin-like protein, GSDMB, GSDML
Target/Specificity GSDML (AAH25682, 1 a.a. ~ 411 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsGSDML Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.


Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease. Fransen K, et al. Hum Mol Genet, 2010 Sep 1. PMID 20601676.In silico replication of the genome-wide association results of the Type 1 Diabetes Genetics Consortium. Qu HQ, et al. Hum Mol Genet, 2010 Jun 15. PMID 20378605.Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease. Verlaan DJ, et al. Am J Hum Genet, 2009 Sep. PMID 19732864.Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Barrett JC, et al. Nat Genet, 2009 Jun. PMID 19430480.Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma. Wu H, et al. Allergy, 2009 Apr. PMID 19133921.

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$ 315.00
Cat# AT2270a
(40 western blots)
Availability: 7-10 days
Bulk Size
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