HDAC11 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant HDAC11.
|Application ||WB, IF, E|
|Calculated MW||39183 Da|
|Other Names||Histone deacetylase 11, HD11, HDAC11|
|Target/Specificity||HDAC11 (AAH09676, 1 a.a. ~ 347 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||HDAC11 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.
Differential histone deacetylase mRNA expression patterns in amyotrophic lateral sclerosis. Janssen C, et al. J Neuropathol Exp Neurol, 2010 Jun. PMID 20467334. Acetylation/deacetylation modulates the stability of DNA replication licensing factor Cdt1. Glozak MA, et al. J Biol Chem, 2009 Apr 24. PMID 19276081. From immunity to tolerance through HDAC. Georgopoulos K. Nat Immunol, 2009 Jan. PMID 19088734. The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance. Villagra A, et al. Nat Immunol, 2009 Jan. PMID 19011628. MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo. Fournel M, et al. Mol Cancer Ther, 2008 Apr. PMID 18413790.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.