HHIP Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant HHIP.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IP |
---|---|
Primary Accession | Q96QV1 |
Other Accession | NM_022475 |
Reactivity | Human |
Host | mouse |
Clonality | Monoclonal |
Isotype | IgG2b Kappa |
Clone Names | 5D11 |
Calculated MW | 78851 Da |
Gene ID | 64399 |
---|---|
Other Names | Hedgehog-interacting protein, HHIP, HIP, HHIP, HIP |
Target/Specificity | HHIP (NP_071920, 21 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | HHIP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein similar to the mouse hedgehog-interacting protein, a regulatory component of the hedgehog signalling pathway. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic development, including anteroposterior patterns of limbs and regulation of left-right asymmetry.
References
1.Role of hedgehog signaling in malignant pleural mesothelioma.Shi Y, Moura U, Opitz I, Soltermann A, Rehrauer H, Thies S, Weder W, Stahel RA, Felley-Bosco E.Clin Cancer Res. 2012 Sep 1;18(17):4646-56. Epub 2012 Jun 25.
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