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>   home   >   Products   >   Primary Antibodies   >   HIC1 Antibody (monoclonal) (M01)   

HIC1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant HIC1.

  • WB - HIC1 Antibody (monoclonal) (M01) AT2367a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (32.38 KDa) .
  • WB - HIC1 Antibody (monoclonal) (M01) AT2367a
    HIC1 monoclonal antibody (M01), clone 4E11. Western Blot analysis of HIC1 expression in PC-12((Cat # AT2367a )
  • WB - HIC1 Antibody (monoclonal) (M01) AT2367a
    HIC1 monoclonal antibody (M01), clone 4E11 Western Blot analysis of HIC1 expression in Jurkat ( (Cat # AT2367a )
  • IF - HIC1 Antibody (monoclonal) (M01) AT2367a
    Immunofluorescence of monoclonal antibody to HIC1 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - HIC1 Antibody (monoclonal) (M01) AT2367a
    Detection limit for recombinant GST tagged HIC1 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14526
Other Accession NM_006497
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 4E12
Calculated MW 76508 Da
Additional Information
Gene ID 3090
Other Names Hypermethylated in cancer 1 protein, Hic-1, Zinc finger and BTB domain-containing protein 29, HIC1, ZBTB29
Target/Specificity HIC1 (NP_006488, 396 a.a. ~ 453 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsHIC1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants.


Gene methylation of SFRP2, P16, DAPK1, HIC1, and MGMT and KRAS mutations in sporadic colorectal cancer. Pehlivan S, et al. Cancer Genet Cytogenet, 2010 Sep. PMID 20682398.Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells. Van Rechem C, et al. Mol Cell Biol, 2010 Aug. PMID 20547755.A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1. Zhang W, et al. Oncogene, 2010 Apr 29. PMID 20154726.HIC1 regulates tumor cell responses to endocrine therapies. Zhang B, et al. Mol Endocrinol, 2009 Dec. PMID 19819984.

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$ 315.00
Cat# AT2367a
(40 western blots)
Availability: 7-10 days
Bulk Size
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