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ICA1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant ICA1.

  • WB - ICA1 Antibody (monoclonal) (M01) AT2467a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - ICA1 Antibody (monoclonal) (M01) AT2467a
    Western Blot analysis of ICA1 expression in transfected 293T cell line by ICA1 monoclonal antibody (M01), clone 6G11.

    Lane 1: ICA1 transfected lysate (Predicted MW: 54.6 KDa).
    Lane 2: Non-transfected lysate.
  • E - ICA1 Antibody (monoclonal) (M01) AT2467a
    Detection limit for recombinant GST tagged ICA1 is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q05084
Other Accession NM_022307
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 6G11
Calculated MW 54645 Da
Additional Information
Gene ID 3382
Other Names Islet cell autoantigen 1, 69 kDa islet cell autoantigen, ICA69, Islet cell autoantigen p69, ICAp69, p69, ICA1
Target/Specificity ICA1 (NP_071682, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsICA1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.


Common variants in FOXP1 are associated with generalized vitiligo. Jin Y, et al. Nat Genet, 2010 Jul. PMID 20526340. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. ICA69 is a novel Rab2 effector regulating ER-Golgi trafficking in insulinoma cells. Buffa L, et al. Eur J Cell Biol, 2008 Apr. PMID 18187231. Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931. The LIFEdb database in 2006. Mehrle A, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381901.

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$ 315.00
Cat# AT2467a
(40 western blots)
Availability: 7-10 days
Bulk Size
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