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IL10 Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant IL10.

  • WB - IL10 Antibody (monoclonal) (M03) AT2500a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.29 KDa) .
  • WB - IL10 Antibody (monoclonal) (M03) AT2500a
    Western Blot analysis of IL10 expression in transfected 293T cell line by IL10 monoclonal antibody (M03), clone 1C10.

    Lane 1: IL10 transfected lysate(20.5 KDa).
    Lane 2: Non-transfected lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P22301
Other Accession NM_000572
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG3 Kappa
Clone Names 1C10
Calculated MW 20517 Da
Additional Information
Gene ID 3586
Other Names Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF, IL10
Target/Specificity IL10 (AAI04253.1, 74 a.a. ~ 178 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsIL10 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.


Association of Interleukin-10 Polymorphisms with Cytokines in Type 2 Diabetic Nephropathy. Kung WJ, et al. Diabetes Technol Ther, 2010 Sep 1. PMID 20809684.Interleukin-10 microsatellite variants and the risk of acute coronary syndrome among Tunisians. Ben-Hadj-Khalifa-Kechiche S, et al. Int J Immunogenet, 2010 Aug 29. PMID 20807264.Intereleukin-10 promoter polymorphism in mild cognitive impairment and in its clinical evolution. Arosio B, et al. Int J Alzheimers Dis, 2010 Jul 20. PMID 20798845.The associations between two polymorphisms in the interleukin-10 gene promoter and breast cancer risk. Yu KD, et al. Breast Cancer Res Treat, 2010 Aug 25. PMID 20737205.Association of genetic polymorphisms in the interleukin-10 promoter with risk of prostate cancer in Chinese. Liu J, et al. BMC Cancer, 2010 Aug 24. PMID 20735825.

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$ 315.00
Cat# AT2500a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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