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IL1A Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant IL1A.

  • WB - IL1A Antibody (monoclonal) (M01) AT2508a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - IL1A Antibody (monoclonal) (M01) AT2508a
    Western Blot analysis of IL1A expression in transfected 293T cell line by IL1A monoclonal antibody (M01), clone 4B8.

    Lane 1: IL1A transfected lysate(30.6 KDa).
    Lane 2: Non-transfected lysate.
  • E - IL1A Antibody (monoclonal) (M01) AT2508a
    Detection limit for recombinant GST tagged IL1A is approximately 3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01583
Other Accession BC013142
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 4B8
Calculated MW 30607 Da
Additional Information
Gene ID 3552
Other Names Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1, IL1A, IL1F1
Target/Specificity IL1A (AAH13142, 172 a.a. ~ 271 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsIL1A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.


CCL3 genotype and current depression increase risk of HIV-associated dementia. Levine AJ, et al. Neurobehav HIV Med, 2009 Nov. PMID 20725607.An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Shimada M, et al. Hum Genet, 2010 Oct. PMID 20677014.A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Romero R, et al. Am J Obstet Gynecol, 2010 Jul 29. PMID 20673868.Interleukin-1A +4845(G>T) polymorphism is a factor predisposing to acne vulgaris. Szab? K, et al. Tissue Antigens, 2010 Jul 11. PMID 20630038.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.

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$ 315.00
Cat# AT2508a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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