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IL1B Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant IL1B.

  • WB - IL1B Antibody (monoclonal) (M01) AT2509a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - IL1B Antibody (monoclonal) (M01) AT2509a
    IL1B monoclonal antibody (M01), clone 2A8. Western Blot analysis of IL1B expression in human liver.
  • IF - IL1B Antibody (monoclonal) (M01) AT2509a
    Immunofluorescence of monoclonal antibody to IL1B on HeLa cell . [antibody concentration 10 ug/ml]
  • IP - IL1B Antibody (monoclonal) (M01) AT2509a
    Immunoprecipitation of IL1B transfected lysate using anti-IL1B monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with IL1B MaxPab rabbit polyclonal antibody.
  • E - IL1B Antibody (monoclonal) (M01) AT2509a
    Detection limit for recombinant GST tagged IL1B is approximately 10ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01584
Other Accession BC008678
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 2A8
Calculated MW 30748 Da
Additional Information
Gene ID 3553
Other Names Interleukin-1 beta, IL-1 beta, Catabolin, IL1B, IL1F2
Target/Specificity IL1B (AAH08678, 170 a.a. ~ 269 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsIL1B Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.


1.Upregulation of MMP-13 via Runx2 in the stromal cell of Giant Cell Tumor.Mak IW, Cowan RW, Popovic S, Colterjohn N, Singh G, Ghert M.Bone. 2009 Aug;45(2):377-86. Epub 2009 May 5.

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$ 315.00
Cat# AT2509a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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