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KCNK10 Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant KCNK10.

  • WB - KCNK10 Antibody (monoclonal) (M03) AT2600a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • E - KCNK10 Antibody (monoclonal) (M03) AT2600a
    Detection limit for recombinant GST tagged KCNK10 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P57789
Other Accession NM_021161
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1C1
Calculated MW 59765 Da
Additional Information
Gene ID 54207
Other Names Potassium channel subfamily K member 10, Outward rectifying potassium channel protein TREK-2, TREK-2 K(+) channel subunit, KCNK10, TREK2
Target/Specificity KCNK10 (NP_066984, 439 a.a. ~ 538 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsKCNK10 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.


Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein. Gierten J, et al. Br J Pharmacol, 2008 Aug. PMID 18516069.Recent advance and possible future in TREK-2: a two-pore potassium channel may involved in the process of NPP, brain ischemia and memory impairment. Huang D, et al. Med Hypotheses, 2008. PMID 17689202.International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. Goldstein SA, et al. Pharmacol Rev, 2005 Dec. PMID 16382106.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2. Gu W, et al. J Physiol, 2002 Mar 15. PMID 11897838.

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$ 315.00
Cat# AT2600a
(40 western blots)
Availability: 7-10 days
Bulk Size
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