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KRT20 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant KRT20.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF |
|---|---|
| Primary Accession | P35900 |
| Other Accession | BC031559 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 2G3-1C8 |
| Calculated MW | 48487 Da |
| Gene ID | 54474 |
|---|---|
| Other Names | Keratin, type I cytoskeletal 20, Cytokeratin-20, CK-20, Keratin-20, K20, Protein IT, KRT20 |
| Target/Specificity | KRT20 (AAH31559, 1 a.a. ~ 424 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | KRT20 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
References
The clinical implications of MMP-11 and CK-20 expression in human breast cancer. Cheng CW, et al. Clin Chim Acta, 2010 Feb. PMID 19914229. Identification of 15 loci influencing height in a Korean population. Kim JJ, et al. J Hum Genet, 2010 Jan. PMID 19893584. Aberrant expression of class III beta-tubulin in basal cell carcinoma of the skin. Ishida M, et al. Oncol Rep, 2009 Oct. PMID 19724850. [Association of CK20 expression with the progression, metastasis and prognosis of breast cancer] Wang SM, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2009 Aug. PMID 19664394. Detection of epithelial cells by RT-PCR targeting CEA, CK20, and TEM-8 in colorectal carcinoma patients using OncoQuick density gradient centrifugation system. Lagoudianakis EE, et al. J Surg Res, 2009 Aug. PMID 19645077.
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