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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MAPKAPK3 Antibody (monoclonal) (M02)   

MAPKAPK3 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant MAPKAPK3.

  • WB - MAPKAPK3 Antibody (monoclonal) (M02) AT2796a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - MAPKAPK3 Antibody (monoclonal) (M02) AT2796a
    MAPKAPK3 monoclonal antibody (M02), clone 2B5 Western Blot analysis of MAPKAPK3 expression in HeLa ( (Cat # AT2796a )
  • WB - MAPKAPK3 Antibody (monoclonal) (M02) AT2796a
    MAPKAPK3 monoclonal antibody (M02), clone 2B5. Western Blot analysis of MAPKAPK3 expression in NIH/3T3 ( (Cat # AT2796a )
  • IHC - MAPKAPK3 Antibody (monoclonal) (M02) AT2796a
    Immunoperoxidase of monoclonal antibody to MAPKAPK3 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
  • E - MAPKAPK3 Antibody (monoclonal) (M02) AT2796a
    Detection limit for recombinant GST tagged MAPKAPK3 is approximately 0.03ng/ml as a capture antibody.
  •  - MAPKAPK3 Antibody (monoclonal) (M02) AT2796a
    Proximity Ligation Analysis of protein-protein interactions between MAPK13 and MAPKAPK3 HeLa cells were stained with anti-MAPK13 rabbit purified polyclonal 1:1200 and anti-MAPKAPK3 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16644
Other Accession BC001662
Reactivity Human, Mouse
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2B5
Calculated MW 42987 Da
Additional Information
Gene ID 7867
Other Names MAP kinase-activated protein kinase 3, MAPK-activated protein kinase 3, MAPKAP kinase 3, MAPKAP-K3, MAPKAPK-3, MK-3, Chromosome 3p kinase, 3pK, MAPKAPK3
Target/Specificity MAPKAPK3 (AAH01662, 272 a.a. ~ 382 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMAPKAPK3 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.High-resolution crystal structure of human Mapkap kinase 3 in complex with a high affinity ligand. Cheng R, et al. Protein Sci, 2010 Jan. PMID 19937655.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population. So HC, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jan 5. PMID 19367581.A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C. Tsukada H, et al. Gastroenterology, 2009 May. PMID 19208361.

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$ 315.00
Cat# AT2796a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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