MAPRE2 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a partial recombinant MAPRE2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IF |
---|---|
Primary Accession | Q15555 |
Other Accession | NM_014268 |
Reactivity | Human |
Host | mouse |
Clonality | Monoclonal |
Isotype | IgG1 Kappa |
Clone Names | 4D7 |
Calculated MW | 37031 Da |
Gene ID | 10982 |
---|---|
Other Names | Microtubule-associated protein RP/EB family member 2, APC-binding protein EB2, End-binding protein 2, EB2, MAPRE2, RP1 |
Target/Specificity | MAPRE2 (NP_055083, 1 a.a. ~ 62 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | MAPRE2 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. The function of this protein is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR. Alternative splicing results in multiple transcript variants.
References
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Molecular insights into mammalian end-binding protein heterodimerization. De Groot CO, et al. J Biol Chem, 2010 Feb 19. PMID 20008324.The microtubule-associated protein MAPRE2 is involved in perineural invasion of pancreatic cancer cells. Abiatari I, et al. Int J Oncol, 2009 Nov. PMID 19787265.Interactions between EB1 and microtubules: dramatic effect of affinity tags and evidence for cooperative behavior. Zhu ZC, et al. J Biol Chem, 2009 Nov 20. PMID 19778897.Suppression of microtubule dynamic instability by the +TIP protein EB1 and its modulation by the CAP-Gly domain of p150glued. Manna T, et al. Biochemistry, 2008 Jan 15. PMID 18081319.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.