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MCC Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant MCC.

  • WB - MCC Antibody (monoclonal) (M01) AT2815a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - MCC Antibody (monoclonal) (M01) AT2815a
    Western Blot analysis of MCC expression in transfected 293T cell line by MCC monoclonal antibody (M01), clone 1A7.

    Lane 1: MCC transfected lysate(93.1 KDa).
    Lane 2: Non-transfected lysate.
  • E - MCC Antibody (monoclonal) (M01) AT2815a
    Detection limit for recombinant GST tagged MCC is approximately 0.03ng/ml as a capture antibody.
  • WB - MCC Antibody (monoclonal) (M01) AT2815a
    Western blot analysis of MCC over-expressed 293 cell line, cotransfected with MCC Validated Chimera RNAi ( (Cat # AT2815a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23508
Other Accession BC009279
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1A7
Calculated MW 93027 Da
Additional Information
Gene ID 4163
Other Names Colorectal mutant cancer protein, Protein MCC, MCC
Target/Specificity MCC (AAH09279, 31 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMCC Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.


Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Association of genetic variants with hemorrhagic stroke in Japanese individuals. Yoshida T, et al. Int J Mol Med, 2010 Apr. PMID 20198315.Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. Oguri M, et al. Am J Hypertens, 2010 Jan. PMID 19851296.MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells. Arnaud C, et al. FEBS Lett, 2009 Jul 21. PMID 19555689.Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription. Fukuyama R, et al. Oncogene, 2008 Oct 9. PMID 18591935.

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$ 315.00
Cat# AT2815a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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