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  • Catalog #

MEF2A Antibody (monoclonal) (M15)Purified Mouse Monoclonal Antibody (Mab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AT2835a 100 ug 400 ul 7-10 days $ 315.00 Add to cart
  • Specification
  • Citiations : 0
  • Reviews
  • Protocols
  • Backgrounds

MEF2A Antibody (monoclonal) (M15) - Product info

ApplicationIF, WB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ02078
ReactivityHuman
IsotypeIgG2a Kappa
Clone Names1C8
Calculated MW54811 Da

MEF2A Antibody (monoclonal) (M15) - Additional info

Gene ID 4205
Other Names
ADCAD1, RSRFC4, RSRFC9MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)
Target/Specificity
MEF2A (AAH13437, 71 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution
WB~~1:500~1000
Format
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
MEF2A Antibody (monoclonal) (M15) is for research use only and not for use in diagnostic or therapeutic procedures.

MEF2A Antibody (monoclonal) (M15) - Related products

AP9258c: MEF2A Antibody (Center)

RI13273: MEF2A predesign siRNA

DC07985: Human MEF2A cDNA Clone

LY11555a: MEF2A Over-expression Lysate

BP9258c: MEF2A Antibody (Center) Blocking Peptide

AT2834a: MEF2A Antibody (monoclonal) (M08)

AT2835a: MEF2A Antibody (monoclonal) (M15)

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.

REFERENCES

COMMON VARIANTS IN 40 GENES ASSESSED FOR DIABETES INCIDENCE AND RESPONSE TO METFORMIN AND LIFESTYLE INTERVENTIONS IN THE DIABETES PREVENTION PROGRAM. Jablonski KA, et al. Diabetes, 2010 Aug 3. PMID 20682687.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Dual roles for MEF2A and MEF2D during human macrophage terminal differentiation and c-Jun expression. Aude-Garcia C, et al. Biochem J, 2010 Sep 1. PMID 20590529.Structural changes in exon 11 of MEF2A are not related to sporadic coronary artery disease in Han Chinese population. Dai DP, et al. Eur J Clin Invest, 2010 Aug. PMID 20546016.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.