MFRP Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant MFRP.
|Application ||WB, IF, E|
|Calculated MW||25298 Da|
|Other Names||Complement C1q tumor necrosis factor-related protein 5, C1QTNF5, CTRP5|
|Target/Specificity||MFRP (NP_113621, 480 a.a. ~ 579 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||MFRP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes a member of the frizzled-related proteins. The encoded protein may play a role in eye development, as mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic mRNA, which also encodes C1q and tumor necrosis factor related protein 5.
A detailed phenotypic assessment of individuals affected by MFRP-related oculopathy. Mukhopadhyay R, et al. Mol Vis, 2010 Mar 26. PMID 20361016.Compound heterozygosity for a novel and a recurrent MFRP gene mutation in a family with the nanophthalmos-retinitis pigmentosa complex. Zenteno JC, et al. Mol Vis, 2009 Sep 5. PMID 19753314.Evaluation of MFRP as a candidate gene for high hyperopia. Wang P, et al. Mol Vis, 2009. PMID 19169412.The association of membrane frizzled-related protein (MFRP) gene with acute angle-closure glaucoma--a pilot study. Wang IJ, et al. Mol Vis, 2008 Sep 8. PMID 18781223.Molecular analysis of CHX10 and MFRP in Chinese subjects with primary angle closure glaucoma and short axial length eyes. Aung T, et al. Mol Vis, 2008 Jul 17. PMID 18648522.
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