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MPZ Antibody (monoclonal) (M05)

Mouse monoclonal antibody raised against a full length recombinant MPZ.

  • E - MPZ Antibody (monoclonal) (M05) AT2897a
    Detection limit for recombinant GST tagged MPZ is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P25189
Other Accession BC006491
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3B12
Calculated MW 27555 Da
Additional Information
Gene ID 4359
Other Names Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero, MPZ
Target/Specificity MPZ (AAH06491.1, 1 a.a. ~ 258 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMPZ Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies.


Charcot-Marie-Tooth disease with intermediate conduction velocities caused by a novel mutation in the MPZ gene. Banchs I, et al. Muscle Nerve, 2010 Aug. PMID 20544920.Charcot-Marie-Tooth disease due to novel myelin protein zero mutation presenting as late-onset remitting sensory neuropathy. Simpson BS, et al. J Clin Neuromuscul Dis, 2010 Jun. PMID 20516806.Asymmetric phenotype associated with rare myelin protein zero mutation. Souayah N, et al. J Clin Neuromuscul Dis, 2010 Mar. PMID 20215982.Laryngeal neuropathy of Charcot-Marie-Tooth disease: further observations and novel mutations associated with vocal fold paresis. Benson B, et al. Laryngoscope, 2010 Feb. PMID 19950375.[Predominant parasympathetic involvement in a patient with Charcot-Marie-Tooth disease caused by the MPZ Thr124Met mutation] Nakamura N, et al. Rinsho Shinkeigaku, 2009 Sep. PMID 19928689.

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$ 315.00
Cat# AT2897a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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