|Application ||WB, E|
|Calculated MW||39366 Da|
|Other Names||Major histocompatibility complex class I-related gene protein, MHC class I-related gene protein, Class I histocompatibility antigen-like protein, MR1|
|Target/Specificity||MR1 (NP_001522, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||MR1 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496. The MHC-related protein 1 (MR1) is expressed by a subpopulation of CD38+, IgA+ cells in the human intestinal mucosa. Gozalbo-L?pez B, et al. Histol Histopathol, 2009 Nov. PMID 19760593. Identification of 4 new HLA-DR-restricted minor histocompatibility antigens as hematopoietic targets in antitumor immunity. Stumpf AN, et al. Blood, 2009 Oct 22. PMID 19706888. MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution. Huang S, et al. Proc Natl Acad Sci U S A, 2009 May 19. PMID 19416870. Novel MHC class I-related molecule MR1 affects MHC class I expression in 293T cells. Aldemir H. Biochem Biophys Res Commun, 2008 Feb 8. PMID 18068122.
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