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>   home   >   Products   >   Primary Antibodies   >   MSH5 Antibody (monoclonal) (M08)   

MSH5 Antibody (monoclonal) (M08)

Mouse monoclonal antibody raised against a partial recombinant MSH5.

     
  • WB - MSH5 Antibody (monoclonal) (M08) AT2911a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • IF - MSH5 Antibody (monoclonal) (M08) AT2911a
    Immunofluorescence of monoclonal antibody to MSH5 on HeLa cell . [antibody concentration 10 ug/ml]
  • E - MSH5 Antibody (monoclonal) (M08) AT2911a
    Detection limit for recombinant GST tagged MSH5 is approximately 0.1ng/ml as a capture antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, E
Primary Accession O43196
Other Accession BC002498
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1C11
Calculated MW 92875 Da
Additional Information
Gene ID 4439
Other Names MutS protein homolog 5, hMSH5, MSH5
Target/Specificity MSH5 (AAH02498, 736 a.a. ~ 835 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMSH5 Antibody (monoclonal) (M08) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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Background

This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms heterooligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants.

References

1.Spermatogenesis-specific association of SMCY and MSH5.Akimoto C, Kitagawa H, Matsumoto T, Kato S.Genes Cells. 2008 Jun;13(6):623-33. Epub 2008 May 4.

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$ 315.00
Cat# AT2911a
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