MSH5 Antibody (monoclonal) (M08)
Mouse monoclonal antibody raised against a partial recombinant MSH5.
|Application ||WB, IF, E|
|Calculated MW||92875 Da|
|Other Names||MutS protein homolog 5, hMSH5, MSH5|
|Target/Specificity||MSH5 (AAH02498, 736 a.a. ~ 835 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||MSH5 Antibody (monoclonal) (M08) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms heterooligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants.
1.Spermatogenesis-specific association of SMCY and MSH5.Akimoto C, Kitagawa H, Matsumoto T, Kato S.Genes Cells. 2008 Jun;13(6):623-33. Epub 2008 May 4.
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