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MYCN Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant MYCN.

  • WB - MYCN Antibody (monoclonal) (M01) AT2948a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - MYCN Antibody (monoclonal) (M01) AT2948a
    MYCN monoclonal antibody (M01), clone 3H4 Western Blot analysis of MYCN expression in HepG2 ( (Cat # AT2948a )
  • WB - MYCN Antibody (monoclonal) (M01) AT2948a
    Western Blot analysis of MYCN expression in transfected 293T cell line by MYCN monoclonal antibody (M01), clone 3H4.

    Lane 1: MYCN transfected lysate(49.6 KDa).
    Lane 2: Non-transfected lysate.
  • E - MYCN Antibody (monoclonal) (M01) AT2948a
    Detection limit for recombinant GST tagged MYCN is approximately 0.03ng/ml as a capture antibody.
  • WB - MYCN Antibody (monoclonal) (M01) AT2948a
    Western blot analysis of MYCN over-expressed 293 cell line, cotransfected with MYCN Validated Chimera RNAi ( (Cat # AT2948a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04198
Other Accession NM_005378
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3H4
Calculated MW 49561 Da
Additional Information
Gene ID 4613
Other Names N-myc proto-oncogene protein, Class E basic helix-loop-helix protein 37, bHLHe37, MYCN, BHLHE37, NMYC
Target/Specificity MYCN (NP_005369, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMYCN Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.


Analysis of the REL, BCL11A, and MYCN proto-oncogenes belonging to the 2p amplicon in chronic lymphocytic leukemia. Deambrogi C, et al. Am J Hematol, 2010 Jul. PMID 20575024.Pleiotropic role for MYCN in medulloblastoma. Swartling FJ, et al. Genes Dev, 2010 May 15. PMID 20478998.Transcriptional repression of SKP2 is impaired in MYCN-amplified neuroblastoma. Muth D, et al. Cancer Res, 2010 May 1. PMID 20424123.MicroRNA-184 inhibits neuroblastoma cell survival through targeting the serine/threonine kinase AKT2. Foley NH, et al. Mol Cancer, 2010 Apr 21. PMID 20409325.Subtype-specific FBXW7 mutation and MYCN copy number gain in Wilms' tumor. Williams RD, et al. Clin Cancer Res, 2010 Apr 1. PMID 20332316.

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$ 315.00
Cat# AT2948a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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