NDE1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant NDE1.
|Application ||WB, IF, E|
|Calculated MW||38808 Da|
|Other Names||Nuclear distribution protein nudE homolog 1, NudE, NDE1, NUDE|
|Target/Specificity||NDE1 (AAH01421, 1 a.a. ~ 335 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||NDE1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Alternative splicing results in multiple transcript variants.
1.NDE1, NDEL1: Multimerisation, alternate splicing and DISC1 interaction.Bradshaw NJ, Christie S, Soares DC, Carlyle BC, Porteous DJ, Millar JK.Neurosci Lett. 2009 Jan 16;449(3):228-33. Epub 2008 Nov 6.
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