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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NDUFS4 Antibody (monoclonal) (M01)   

NDUFS4 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant NDUFS4.

  • WB - NDUFS4 Antibody (monoclonal) (M01) AT3007a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - NDUFS4 Antibody (monoclonal) (M01) AT3007a
    NDUFS4 monoclonal antibody (M01), clone 1A1 Western Blot analysis of NDUFS4 expression in A-431 ( (Cat # AT3007a )
  • WB - NDUFS4 Antibody (monoclonal) (M01) AT3007a
    Western Blot analysis of NDUFS4 expression in transfected 293T cell line by NDUFS4 monoclonal antibody (M01), clone 1A1.

    Lane 1: NDUFS4 transfected lysate(20.1 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - NDUFS4 Antibody (monoclonal) (M01) AT3007a
    Immunoperoxidase of monoclonal antibody to NDUFS4 on formalin-fixed paraffin-embedded human colon. [antibody concentration 1 ug/ml]
  • E - NDUFS4 Antibody (monoclonal) (M01) AT3007a
    Detection limit for recombinant GST tagged NDUFS4 is approximately 0.3ng/ml as a capture antibody.
  • WB - NDUFS4 Antibody (monoclonal) (M01) AT3007a
    Western blot analysis of NDUFS4 over-expressed 293 cell line, cotransfected with NDUFS4 Validated Chimera RNAi ( (Cat # AT3007a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43181
Other Accession NM_002495
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1A1
Calculated MW 20108 Da
Additional Information
Gene ID 4724
Other Names NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial, Complex I-18 kDa, CI-18 kDa, Complex I-AQDQ, CI-AQDQ, NADH-ubiquinone oxidoreductase 18 kDa subunit, NDUFS4
Target/Specificity NDUFS4 (NP_002486, 66 a.a. ~ 175 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsNDUFS4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes.


NDUFS4 mutations cause Leigh syndrome with predominant brainstem involvement. Leshinsky-Silver E, et al. Mol Genet Metab, 2009 Jul. PMID 19364667.Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. Saito A, et al. J Hum Genet, 2009 Jun. PMID 19343046.Polymorphisms in mitochondrial genes and prostate cancer risk. Wang L, et al. Cancer Epidemiol Biomarkers Prev, 2008 Dec. PMID 19064571.Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. Starr JM, et al. Mech Ageing Dev, 2008 Dec. PMID 18977241.The regulation of PTC containing transcripts of the human NDUFS4 gene of complex I of respiratory chain and the impact of pathological mutations. Panelli D, et al. Biochimie, 2008 Oct. PMID 18555024.

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$ 315.00
Cat# AT3007a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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