NID1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant NID1.
|Application ||WB, E|
|Calculated MW||136377 Da|
|Other Names||Nidogen-1, NID-1, Entactin, NID1, NID|
|Target/Specificity||NID1 (NP_002499.1, 1148 a.a. ~ 1247 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||NID1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix.
Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer. Ulazzi L, et al. Mol Cancer, 2007 Feb 28. PMID 17328794.Lack of nidogen-1 and -2 prevents basement membrane assembly in skin-organotypic coculture. Nischt R, et al. J Invest Dermatol, 2007 Mar. PMID 17008882.The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414.Identification of the basement membrane protein nidogen as a candidate ligand for tumor endothelial marker 7 in vitro and in vivo. Lee HK, et al. FEBS Lett, 2006 Apr 17. PMID 16574105.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.
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