NME2 Antibody (monoclonal) (M11)
Mouse monoclonal antibody raised against a partial recombinant NME2.
|Application ||WB, IF|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||17298 Da|
|Other Names||Nucleoside diphosphate kinase B, NDK B, NDP kinase B, C-myc purine-binding transcription factor PUF, Histidine protein kinase NDKB, nm23-H2, NME2, NM23B|
|Target/Specificity||NME2 (NP_002503, 51 a.a. ~ 152 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||NME2 Antibody (monoclonal) (M11) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Co-transcription of this gene and the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) which encode a fusion protein comprised of sequence sharing identity with each individual gene product.
Nme protein family evolutionary history, a vertebrate perspective. Desvignes T, et al. BMC Evol Biol, 2009 Oct 23. PMID 19852809.Identification and functional characterization of cytoplasmic determinants of plasmid DNA nuclear import. Munkonge FM, et al. J Biol Chem, 2009 Sep 25. PMID 19638341.Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis. Treharne KJ, et al. FEBS Lett, 2009 Sep 3. PMID 19619546.Role of nm23 in the regulation of cell shape and migration via Rho family GTPase signals. Miyamoto M, et al. Mol Cell Biochem, 2009 Sep. PMID 19381785.NM23H2 inhibits EGF- and Ras-induced proliferation of NIH3T3 cells by blocking the ERK pathway. Lee MY, et al. Cancer Lett, 2009 Mar 18. PMID 19022560.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.