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PDCD11 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant PDCD11.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q14690 |
| Other Accession | BC049838 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 3.0E+12 |
| Calculated MW | 208701 Da |
| Gene ID | 22984 |
|---|---|
| Other Names | Protein RRP5 homolog, NF-kappa-B-binding protein, NFBP, Programmed cell death protein 11, PDCD11, KIAA0185 |
| Target/Specificity | PDCD11 (AAH49838, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | PDCD11 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).
References
A novel small-subunit processome assembly intermediate that contains the U3 snoRNP, nucleolin, RRP5, and DBP4. Turner AJ, et al. Mol Cell Biol, 2009 Jun. PMID 19332556.Evidence for involvement of NFBP in processing of ribosomal RNA. Sweet T, et al. J Cell Physiol, 2008 Feb. PMID 17654514.Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.Interplay between NFBP and NF-kappaB modulates tat activation of the LTR. Sweet T, et al. J Cell Physiol, 2005 Aug. PMID 15887232.
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