POU6F1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant POU6F1.
|Application ||WB, E|
|Calculated MW||32645 Da|
|Other Names||POU domain, class 6, transcription factor 1, Brain-specific homeobox/POU domain protein 5, Brain-5, Brn-5, mPOU homeobox protein, POU6F1, BRN5, MPOU, TCFB1|
|Target/Specificity||POU6F1 (NP_002693, 193 a.a. ~ 301 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||POU6F1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Transcription factor POU6F1 is important for proliferation of clear cell adenocarcinoma of the ovary and is a potential new molecular target. Suzuki N, et al. Int J Gynecol Cancer, 2010 Feb. PMID 20134265.POU6F1 is the transcription factor that might be involved in cell proliferation of clear cell adenocarcinoma of the ovary. Yoshioka N, et al. Hum Cell, 2009 Nov. PMID 19874398.Structure of human Brn-5 transcription factor in complex with CRH gene promoter. Pereira JH, et al. J Struct Biol, 2009 Aug. PMID 19450691.Crystallization and preliminary X-ray analysis of human Brn-5 transcription factor in complex with DNA. Pereira JH, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2008 Mar 1. PMID 18323601.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.
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