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PPA1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant PPA1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q15181 |
| Other Accession | NM_021129 |
| Reactivity | Human, Rat |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 3B2 |
| Calculated MW | 32660 Da |
| Gene ID | 5464 |
|---|---|
| Other Names | Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase, PPA1, IOPPP, PP |
| Target/Specificity | PPA1 (NP_066952, 10 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | PPA1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme.
References
Localization of the structural genes for hexokinase-1 and inorganic pyrophosphatase on region (pter-->q24) of human chromosome 10. Chern CJ. Cytogenet Cell Genet, 1976. PMID 17494625.[Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system] Maksimov VV, et al. Genetika, 2006 Feb. PMID 16583711.Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. Guo D, et al. Biochem Biophys Res Commun, 2005 Dec 2. PMID 16236267.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis. Bruneel A, et al. Proteomics, 2005 Oct. PMID 16130169.
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