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>   home   >   Products   >   Primary Antibodies   >   PTRF Antibody (monoclonal) (M02)   

PTRF Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant PTRF.

  • IHC - PTRF Antibody (monoclonal) (M02) AT3498a
    Immunoperoxidase of monoclonal antibody to PTRF on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6NZI2
Other Accession NM_012232
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 1F7
Calculated MW 43476 Da
Additional Information
Gene ID 284119
Other Names Polymerase I and transcript release factor, Cavin-1, PTRF {ECO:0000312|EMBL:AAH661231}
Target/Specificity PTRF (NP_036364, 233 a.a. ~ 321 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsPTRF Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.


1.SDPR induces membrane curvature and functions in the formation of caveolae.Hansen CG, Bright NA, Howard G, Nichols BJ.Nat Cell Biol. 2009 Jul;11(7):807-14. Epub 2009 Jun 14.

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$ 315.00
Cat# AT3498a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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