RALGDS Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RALGDS.
|Calculated MW||100607 Da|
|Other Names||Ral guanine nucleotide dissociation stimulator, RalGDS, Ral guanine nucleotide exchange factor, RalGEF, RALGDS, KIAA1308, RGF|
|Target/Specificity||RALGDS (AAH59362, 793 a.a. ~ 902 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RALGDS Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Ras classical effectors: new tales from in silico complexes. Fuentes G, et al. Trends Biochem Sci, 2009 Nov. PMID 19801192.RalA functions as an indispensable signal mediator for the nutrient-sensing system. Maehama T, et al. J Biol Chem, 2008 Dec 12. PMID 18948269.Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells. Rondaij MG, et al. Blood, 2008 Jul 1. PMID 18417737.No evidence of RALGDS mutations in cutaneous melanoma. Omholt K, et al. Melanoma Res, 2007 Dec. PMID 17992125.Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone. Yin J, et al. Mol Cell Biol, 2007 Nov. PMID 17709381.
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