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RBM9 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant RBM9.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, E |
|---|---|
| Primary Accession | O43251 |
| Other Accession | BC013115 |
| Reactivity | Human, Mouse |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 5E12 |
| Calculated MW | 41374 Da |
| Gene ID | 23543 |
|---|---|
| Other Names | RNA binding protein fox-1 homolog 2, Fox-1 homolog B, Hexaribonucleotide-binding protein 2, RNA-binding motif protein 9, RNA-binding protein 9, Repressor of tamoxifen transcriptional activity, RBFOX2, FOX2, HRNBP2, RBM9, RTA |
| Target/Specificity | RBM9 (AAH13115, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RBM9 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
References
Fox-2 protein regulates the alternative splicing of scleroderma-associated lysyl hydroxylase 2 messenger RNA. Seth P, et al. Arthritis Rheum, 2010 Apr. PMID 20131247.An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. Yeo GW, et al. Nat Struct Mol Biol, 2009 Feb. PMID 19136955.Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2. Zhang C, et al. Genes Dev, 2008 Sep 15. PMID 18794351.hnRNP H and hnRNP F complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIc. Mauger DM, et al. Mol Cell Biol, 2008 Sep. PMID 18573884.Repression of prespliceosome complex formation at two distinct steps by Fox-1/Fox-2 proteins. Zhou HL, et al. Mol Cell Biol, 2008 Sep. PMID 18573872.
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